Cart
sales@molnova.com
Folinic acid
CAS No. 58-05-9
Folinic acid( —— )
Catalog No. M33999 CAS No. 58-05-9
Folinic acid (Leucovorin) is a biofolate used in the treatment of methotrexate (MTX) toxicity reduction and as an adjuvant therapy for colon cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 31 | In Stock |
|
| 25MG | 46 | In Stock |
|
| 50MG | 64 | In Stock |
|
| 100MG | 90 | In Stock |
|
| 500MG | 215 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameFolinic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionFolinic acid (Leucovorin) is a biofolate used in the treatment of methotrexate (MTX) toxicity reduction and as an adjuvant therapy for colon cancer.
-
DescriptionFolinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity.
-
In Vitro——
-
In VivoAnimal Model:24 Balb/c young growing male mice aged 3 weeks (11.88 ± 0.25 g)Dosage:7.0 mg/kg Administration:Intraperitoneal injection; every second day; for 3 weeks Result:Following MTX administration appears to reverse this growth inhibition.
-
Synonyms——
-
PathwayProteasome/Ubiquitin
-
TargetEndogenous Metabolite
-
RecptorEndogenous Metabolite | Antifolate
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number58-05-9
-
Formula Weight473.44
-
Molecular FormulaC20H23N7O7
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (528.05 mM; Ultrasonic )
-
SMILESNc1nc2NCC(CNc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)N(C=O)c2c(=O)[nH]1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Keshava, C., et al., Inhibition of methotrexate-induced chromosomal damage by folinic acid in V79 cells. Mutat Res, 1998. 397(2): p. 221-8.?
molnova catalog
related products
-
Stearoylcarnitine
Stearoylcarnitine (Stearoyl-L-carnitine) is a fatty ester lipid molecule, a human endogenous metabolite that serves as a biomarker for early-onset preeclampsia and late-onset preeclampsia.
-
17a-Hydroxypregnenol...
17a-Hydroxypregnenolone is a pregnane steroid. It is a prohormone in the formation of dehydroepiandrosterone (DHEA).
-
5-Methylcytidine
5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms.
